Chemical Compound Libraries
Our chemical library is a collection of stocked chemicals used in high throughput screening, medicinal chemistry, common drug design as well as in chemical research.
Aurora offers about 6.9 million real and stocked compounds. The complete catalog can be downloaded from the download site on our home page. Quite a small part of 100,000 structures can be searched online.
Aurora delivers value through:
- small compound library for drug discovery
- drug-like compounds collection
- state-of-the-art equipment for modern HTP synthesis and analysis
- flexibility to perform in both a high service level as well as a cost efficient solution.
Aurora's targeted library is a set of compounds with a high predictability in silico affinity for a given protein target. Focused libraries dramatically reduce the number of substances for experimental activity assessment and increase the number of really strong inhibitors found among experimentally tested substances.
Our targeted libraries possess an outstanding quality due to the high accuracy of docking and energy calculation. This is possible because a new paradigm in molecular modeling is applying quantum and molecular physics instead of statistical approaches.
Our hit rate for predicted strong inhibitors is about 50%. This means that about 50 compounds from 100 library molecules chosen for experimental activity assessment are real inhibitors.
Features of our focused compounds collection show the following advantages:
- High Affinity
- Compliance with Lipinski's drug-like parameters
- High Selectivity
- Low Toxicity
- Patentability
Our database contains 6.9 million compounds available from stock.
Online Chemical Catalog
Aurora's Whole Download Catalog
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